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LXR-Mediated ABCA1 Expression and Function Are Modulated by High Glucose and PRMT2
High cholesterol and diabetes are major risk factors for atherosclerosis. Regression of atherosclerosis is mediated in part by the Liver X Receptor (LXR) through the induction of genes involved in cholesterol transport and efflux. In the context of diabetes, regression of atherosclerosis is impaired...
Autores principales: | Hussein, Maryem A., Shrestha, Elina, Ouimet, Mireille, Barrett, Tessa J., Leone, Sarah, Moore, Kathryn J., Hérault, Yann, Fisher, Edward A., Garabedian, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545936/ https://www.ncbi.nlm.nih.gov/pubmed/26288135 http://dx.doi.org/10.1371/journal.pone.0135218 |
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