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The Prion Protein Controls Polysialylation of Neural Cell Adhesion Molecule 1 during Cellular Morphogenesis

Despite its multi-faceted role in neurodegenerative diseases, the physiological function of the prion protein (PrP) has remained elusive. On the basis of its evolutionary relationship to ZIP metal ion transporters, we considered that PrP may contribute to the morphogenetic reprogramming of cells und...

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Detalles Bibliográficos
Autores principales: Mehrabian, Mohadeseh, Brethour, Dylan, Wang, Hansen, Xi, Zhengrui, Rogaeva, Ekaterina, Schmitt-Ulms, Gerold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546001/
https://www.ncbi.nlm.nih.gov/pubmed/26288071
http://dx.doi.org/10.1371/journal.pone.0133741