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TMalphaDB and TMbetaDB: web servers to study the structural role of sequence motifs in α-helix and β-barrel domains of membrane proteins

BACKGROUND: Membrane proteins represent over 25 % of human protein genes and account for more than 60 % of drug targets due to their accessibility from the extracellular environment. The increasing number of available crystal structures of these proteins in the Protein Data Bank permits an initial e...

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Detalles Bibliográficos
Autores principales: Perea, Marc, Lugtenburg, Ivar, Mayol, Eduardo, Cordomí, Arnau, Deupí, Xavier, Pardo, Leonardo, Olivella, Mireia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546024/
https://www.ncbi.nlm.nih.gov/pubmed/26289158
http://dx.doi.org/10.1186/s12859-015-0699-5