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Bidirectional role of IL-6 signal in pathogenesis of lung fibrosis

BACKGROUND: Various signals are known to participate in the pathogenesis of lung fibrosis. Our aim was to determine which signal is predominantly mobilized in the early inflammatory phase and thereafter modulates the development of lung fibrosis. METHODS: Mice received a single dose of 3 mg/kg body...

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Detalles Bibliográficos
Autores principales: Kobayashi, Takeshi, Tanaka, Kensuke, Fujita, Tetsuo, Umezawa, Hiroki, Amano, Hiroyuki, Yoshioka, Kento, Naito, Yusuke, Hatano, Masahiko, Kimura, Sadao, Tatsumi, Koichiro, Kasuya, Yoshitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546032/
https://www.ncbi.nlm.nih.gov/pubmed/26289430
http://dx.doi.org/10.1186/s12931-015-0261-z