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Male and female mice show significant differences in hepatic transcriptomic response to 2,3,7,8-tetrachlorodibenzo-p-dioxin

BACKGROUND: 2,3,7,8–tetrachlorodibenzo-p-dixion (TCDD) is the most potent of the dioxin congeners, capable of causing a wide range of toxic effects across numerous animal models. Previous studies have demonstrated that males and females of the same species can display divergent sensitivity phenotype...

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Detalles Bibliográficos
Autores principales: Lee, Jamie, Prokopec, Stephenie D., Watson, John D., Sun, Ren X., Pohjanvirta, Raimo, Boutros, Paul C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546048/
https://www.ncbi.nlm.nih.gov/pubmed/26290441
http://dx.doi.org/10.1186/s12864-015-1840-6