The Axl-Regulating Tumor Suppressor miR-34a Is Increased in ccRCC but Does Not Correlate with Axl mRNA or Axl Protein Levels

BACKGROUND: High expression of the receptor tyrosine kinase Axl is associated with poor prognosis in patients with Renal Cell Carcinoma (RCC), the most common malignancy of the kidney. The miR-34a has been shown to directly regulate Axl in cancer cells. The miR-34a is a mediator of p53-dependent tum...

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Detalles Bibliográficos
Autores principales: Fritz, Helena K., Gustafsson, Anna, Ljungberg, Börje, Ceder, Yvonne, Axelson, Håkan, Dahlbäck, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546115/
https://www.ncbi.nlm.nih.gov/pubmed/26287733
http://dx.doi.org/10.1371/journal.pone.0135991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546115/
https://www.ncbi.nlm.nih.gov/pubmed/26287733
http://dx.doi.org/10.1371/journal.pone.0135991

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