Cargando…

Enhanced oral bioavailability of vancomycin in rats treated with long-term parenteral nutrition

Long-term parenteral nutrition (PN) can induce intestinal atrophy, leading to a loss of epithelial integrity in the small intestines. This change may alter the intestinal permeability of vancomycin (VCM), a non-absorbable antibiotic. The aim of the present study was to investigate the effect of PN o...

Descripción completa

Detalles Bibliográficos
Autores principales: Fukushima, Keizo, Okada, Akira, Hayashi, Yoriko, Ichikawa, Hideki, Nishimura, Asako, Shibata, Nobuhito, Sugioka, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546118/
https://www.ncbi.nlm.nih.gov/pubmed/26312207
http://dx.doi.org/10.1186/s40064-015-1228-8