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Enhanced oral bioavailability of vancomycin in rats treated with long-term parenteral nutrition
Long-term parenteral nutrition (PN) can induce intestinal atrophy, leading to a loss of epithelial integrity in the small intestines. This change may alter the intestinal permeability of vancomycin (VCM), a non-absorbable antibiotic. The aim of the present study was to investigate the effect of PN o...
Autores principales: | Fukushima, Keizo, Okada, Akira, Hayashi, Yoriko, Ichikawa, Hideki, Nishimura, Asako, Shibata, Nobuhito, Sugioka, Nobuyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546118/ https://www.ncbi.nlm.nih.gov/pubmed/26312207 http://dx.doi.org/10.1186/s40064-015-1228-8 |
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