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Lentivirus-mediated shRNA interference of clusterin blocks proliferation, motility, invasion and cell cycle in the ovarian cancer cells

BACKGROUND: In a previous analysis on the patients with ovarian cancers, we have found that clusterin is a biomarker associated with ovarian cancer in vivo and may be a prognostic factor associated with adverse outcome. Here, we explored the effect of lentivirus-mediated shRNA interference of cluste...

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Detalles Bibliográficos
Autores principales: Fu, Yanxia, Lai, Yingrong, Liu, Junfeng, Liu, Xingyang, You, Zeshan, Yang, Guofen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546134/
https://www.ncbi.nlm.nih.gov/pubmed/26293319
http://dx.doi.org/10.1186/s13048-015-0173-z