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Platelet Activation and Thrombus Formation over IgG Immune Complexes Requires Integrin αIIbβ3 and Lyn Kinase

IgG immune complexes contribute to the etiology and pathogenesis of numerous autoimmune disorders, including heparin-induced thrombocytopenia, systemic lupus erythematosus, rheumatoid- and collagen-induced arthritis, and chronic glomerulonephritis. Patients suffering from immune complex-related diso...

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Detalles Bibliográficos
Autores principales: Zhi, Huiying, Dai, Jing, Liu, Junling, Zhu, Jieqing, Newman, Debra K., Gao, Cunji, Newman, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546160/
https://www.ncbi.nlm.nih.gov/pubmed/26291522
http://dx.doi.org/10.1371/journal.pone.0135738