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Polymorphic variation of hypoxia inducible factor-1 A (HIF1A) gene might contribute to the development of knee osteoarthritis: a pilot study

BACKGROUND: Osteoarthritis (OA) is a multifactorial degenerative condition of the whole joint with a complex pathogenesis whose development and progression is significantly mediated by interactions between the joint cartilage and articular tissues, particularly, proinflammatory mediators and oxidati...

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Detalles Bibliográficos
Autores principales: Fernández-Torres, Javier, Hernández-Díaz, Cristina, Espinosa-Morales, Rolando, Camacho-Galindo, Javier, Galindo-Sevilla, Norma del Carmen, López-Macay, Ámbar, Zamudio-Cuevas, Yessica, Martínez-Flores, Karina, Santamaría-Olmedo, Mónica Guadalupe, Pineda, Carlos, Granados, Julio, Martínez-Nava, Gabriela Angélica, Gutiérrez, Marwin, López-Reyes, Alberto G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546180/
https://www.ncbi.nlm.nih.gov/pubmed/26293784
http://dx.doi.org/10.1186/s12891-015-0678-z