Cargando…

5-Carboxylcytosine levels are elevated in human breast cancers and gliomas

BACKGROUND: DNA methylation (5-methylcytosine (5mC)) patterns are often altered in cancers. Ten-eleven translocation (Tet) proteins oxidise 5mC to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC). In addition to their presumptive specific biological roles, these o...

Descripción completa

Detalles Bibliográficos
Autores principales: Eleftheriou, Maria, Pascual, Ana Jimenez, Wheldon, Lee M., Perry, Christina, Abakir, Abdulkadir, Arora, Arvind, Johnson, Andrew D., Auer, Dorothee T., Ellis, Ian O., Madhusudan, Srinivasan, Ruzov, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546187/
https://www.ncbi.nlm.nih.gov/pubmed/26300993
http://dx.doi.org/10.1186/s13148-015-0117-x