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Comprehensive DNA Methylation Analysis Reveals a Common Ten-Gene Methylation Signature in Colorectal Adenomas and Carcinomas

Microarray analysis of promoter hypermethylation provides insight into the role and extent of DNA methylation in the development of colorectal cancer (CRC) and may be co-monitored with the appearance of driver mutations. Colonic biopsy samples were obtained endoscopically from 10 normal, 23 adenoma...

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Detalles Bibliográficos
Autores principales: Patai, Árpád V., Valcz, Gábor, Hollósi, Péter, Kalmár, Alexandra, Péterfia, Bálint, Patai, Árpád, Wichmann, Barnabás, Spisák, Sándor, Barták, Barbara Kinga, Leiszter, Katalin, Tóth, Kinga, Sipos, Ferenc, Kovalszky, Ilona, Péter, Zoltán, Miheller, Pál, Tulassay, Zsolt, Molnár, Béla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546193/
https://www.ncbi.nlm.nih.gov/pubmed/26291085
http://dx.doi.org/10.1371/journal.pone.0133836