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Anti-Inflammatory Effects of Ang-(1-7) in Ameliorating HFD-Induced Renal Injury through LDLr-SREBP2-SCAP Pathway

The angiotensin converting enzyme 2-angiotensin-(1–7)-Mas axis (ACE2-Ang-(1–7)-Mas axis) is reported to participate in lipid metabolism in kidney, but its precise effects and underlying mechanisms remain unknown. We hypothesized that Ang-(1–7) reduces lipid accumulation and improves renal injury thr...

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Detalles Bibliográficos
Autores principales: Zheng, Yaning, Tang, Lin, Huang, Wenhan, Yan, Ruyu, Ren, Feifeng, Luo, Lei, Zhang, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546194/
https://www.ncbi.nlm.nih.gov/pubmed/26291618
http://dx.doi.org/10.1371/journal.pone.0136187