Interleukin-18 Down-Regulates Multidrug Resistance-Associated Protein 2 Expression through Farnesoid X Receptor Associated with Nuclear Factor Kappa B and Yin Yang 1 in Human Hepatoma HepG2 Cells

Multidrug resistance-associated protein 2 (MRP2) plays an important role in bile acid metabolism by transporting toxic organic anion conjugates, including conjugated bilirubin, glutathione, sulfate, and multifarious drugs. MRP2 expression is reduced in cholestatic patients and rodents. However, the...

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Detalles Bibliográficos
Autores principales: Liu, Xiao-cong, Lian, Wei, Zhang, Liang-jun, Feng, Xin-chan, Gao, Yu, Li, Shao-xue, Liu, Chang, Cheng, Ying, Yang, Long, Wang, Xiao-Juan, Chen, Lei, Wang, Rong-quan, Chai, Jin, Chen, Wen-sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546195/
https://www.ncbi.nlm.nih.gov/pubmed/26292095
http://dx.doi.org/10.1371/journal.pone.0136215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546195/
https://www.ncbi.nlm.nih.gov/pubmed/26292095
http://dx.doi.org/10.1371/journal.pone.0136215

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