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Plexin-D1/Semaphorin 3E pathway may contribute to dysregulation of vascular tone control and defective angiogenesis in systemic sclerosis

INTRODUCTION: The vascular and nervous systems have several anatomic and molecular mechanism similarities. Emerging evidence suggests that proteins involved in transmitting axonal guidance cues, including members of class III semaphorin (Sema3) family, play a critical role in blood vessel guidance d...

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Detalles Bibliográficos
Autores principales: Mazzotta, Celestina, Romano, Eloisa, Bruni, Cosimo, Manetti, Mirko, Lepri, Gemma, Bellando-Randone, Silvia, Blagojevic, Jelena, Ibba-Manneschi, Lidia, Matucci-Cerinic, Marco, Guiducci, Serena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546224/
https://www.ncbi.nlm.nih.gov/pubmed/26292963
http://dx.doi.org/10.1186/s13075-015-0749-4