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Altered PCA3 and TMPRSS2-ERG expression in histologically benign regions of cancerous prostates: a systematic, quantitative mRNA analysis in five prostates

BACKGROUND: PCA3 and TMPRSS2-ERG are commonly overexpressed biomarkers in prostate cancer, but reports have emerged demonstrating altered expression also in areas outside the tumour foci in cancerous prostates. Our aim was to measure PCA3 and TMPRSS2-ERG expression systematically in all regions of p...

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Detalles Bibliográficos
Autores principales: Väänänen, Riina-Minna, Ochoa, Natalia Tong, Boström, Peter J., Taimen, Pekka, Pettersson, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546243/
https://www.ncbi.nlm.nih.gov/pubmed/26294063
http://dx.doi.org/10.1186/s12894-015-0077-7