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Knockdown of NAT12/NAA30 reduces tumorigenic features of glioblastoma-initiating cells
BACKGROUND: Glioblastoma (GBM) is the most common primary brain malignancy and confers a dismal prognosis. GBMs harbor glioblastoma-initiating cells (GICs) that drive tumorigenesis and contribute to therapeutic resistance and tumor recurrence. Consequently, there is a strong rationale to target this...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546247/ https://www.ncbi.nlm.nih.gov/pubmed/26292663 http://dx.doi.org/10.1186/s12943-015-0432-z |