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Filling the gap: Micro-C accesses the nucleosomal fiber at 100–1000 bp resolution

The fine three-dimensional structure of the nucleosomal fiber has remained elusive to genome-wide chromosome conformation capture (3C) approaches. A new study mapping contacts at the single nucleosome level (Micro-C) reveals topological interacting domains along budding yeast chromosomes. These doma...

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Detalles Bibliográficos
Autores principales: Mozziconacci, Julien, Koszul, Romain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546249/
https://www.ncbi.nlm.nih.gov/pubmed/26294274
http://dx.doi.org/10.1186/s13059-015-0744-8