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Epithelial–Mesenchymal Transition in Kidney Tubular Epithelial Cells Induced by Globotriaosylsphingosine and Globotriaosylceramide

Fabry disease is a lysosomal storage disorder caused by deficiency of alpha-galactosidase A (α-gal A), which results in the deposition of globotriaosylceramide (Gb3) in the vascular endothelium. Globotriaosylsphingosine (lyso-Gb3), a deacylated Gb3, is also increased in the plasma of patients with F...

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Detalles Bibliográficos
Autores principales: Jeon, Yeo Jin, Jung, Namhee, Park, Joo-Won, Park, Hae-Young, Jung, Sung-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546309/
https://www.ncbi.nlm.nih.gov/pubmed/26291612
http://dx.doi.org/10.1371/journal.pone.0136442