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High-throughput methods for identification of protein-protein interactions involving short linear motifs
Interactions between modular domains and short linear motifs (3–10 amino acids peptide stretches) are crucial for cell signaling. The motifs typically reside in the disordered regions of the proteome and the interactions are often transient, allowing for rapid changes in response to changing stimuli...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546347/ https://www.ncbi.nlm.nih.gov/pubmed/26297553 http://dx.doi.org/10.1186/s12964-015-0116-8 |