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High-throughput methods for identification of protein-protein interactions involving short linear motifs

Interactions between modular domains and short linear motifs (3–10 amino acids peptide stretches) are crucial for cell signaling. The motifs typically reside in the disordered regions of the proteome and the interactions are often transient, allowing for rapid changes in response to changing stimuli...

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Detalles Bibliográficos
Autores principales: Blikstad, Cecilia, Ivarsson, Ylva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546347/
https://www.ncbi.nlm.nih.gov/pubmed/26297553
http://dx.doi.org/10.1186/s12964-015-0116-8