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CD4(+)CD25(hi)FOXP3(+) Regulatory T Cells and Cytokine Responses in Human Schistosomiasis before and after Treatment with Praziquantel

BACKGROUND: Chronic schistosomiasis is associated with T cell hypo-responsiveness and immunoregulatory mechanisms, including induction of regulatory T cells (Tregs). However, little is known about Treg functional capacity during human Schistosoma haematobium infection. METHODOLOGY: CD4(+)CD25(hi)FOX...

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Detalles Bibliográficos
Autores principales: Schmiedel, Yvonne, Mombo-Ngoma, Ghyslain, Labuda, Lucja A., Janse, Jacqueline J., de Gier, Brechje, Adegnika, Ayôla A., Issifou, Saadou, Kremsner, Peter G., Smits, Hermelijn H., Yazdanbakhsh, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546370/
https://www.ncbi.nlm.nih.gov/pubmed/26291831
http://dx.doi.org/10.1371/journal.pntd.0003995