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Loss and Gain of Natural Killer Cell Receptor Function in an African Hunter-Gatherer Population

Modulating natural killer cell functions in human immunity and reproduction are diverse interactions between the killer cell immunoglobulin-like receptors (KIR) of Natural Killer (NK) cells and HLA class I ligands on the surface of tissue cells. Dominant interactions are between KIR2DL1 and the C2 e...

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Detalles Bibliográficos
Autores principales: Hilton, Hugo G., Norman, Paul J., Nemat-Gorgani, Neda, Goyos, Ana, Hollenbach, Jill A., Henn, Brenna M., Gignoux, Christopher R., Guethlein, Lisbeth A., Parham, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546388/
https://www.ncbi.nlm.nih.gov/pubmed/26292085
http://dx.doi.org/10.1371/journal.pgen.1005439