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Loss and Gain of Natural Killer Cell Receptor Function in an African Hunter-Gatherer Population
Modulating natural killer cell functions in human immunity and reproduction are diverse interactions between the killer cell immunoglobulin-like receptors (KIR) of Natural Killer (NK) cells and HLA class I ligands on the surface of tissue cells. Dominant interactions are between KIR2DL1 and the C2 e...
Autores principales: | Hilton, Hugo G., Norman, Paul J., Nemat-Gorgani, Neda, Goyos, Ana, Hollenbach, Jill A., Henn, Brenna M., Gignoux, Christopher R., Guethlein, Lisbeth A., Parham, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546388/ https://www.ncbi.nlm.nih.gov/pubmed/26292085 http://dx.doi.org/10.1371/journal.pgen.1005439 |
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