Engraftment of Human Glioblastoma Cells in Immunocompetent Rats through Acquired Immunosuppression

Transplantation of glioblastoma patient biopsy spheroids to the brain of T cell-compromised Rowett (nude) rats has been established as a representative animal model for human GBMs, with a tumor take rate close to 100%. In immunocompetent littermates however, primary human GBM tissue is invariably re...

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Detalles Bibliográficos
Autores principales: Huszthy, Peter C., Sakariassen, Per Ø., Espedal, Heidi, Brokstad, Karl A., Bjerkvig, Rolf, Miletic, Hrvoje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546393/
https://www.ncbi.nlm.nih.gov/pubmed/26291724
http://dx.doi.org/10.1371/journal.pone.0136089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546393/
https://www.ncbi.nlm.nih.gov/pubmed/26291724
http://dx.doi.org/10.1371/journal.pone.0136089

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