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Engraftment of Human Glioblastoma Cells in Immunocompetent Rats through Acquired Immunosuppression
Transplantation of glioblastoma patient biopsy spheroids to the brain of T cell-compromised Rowett (nude) rats has been established as a representative animal model for human GBMs, with a tumor take rate close to 100%. In immunocompetent littermates however, primary human GBM tissue is invariably re...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546393/ https://www.ncbi.nlm.nih.gov/pubmed/26291724 http://dx.doi.org/10.1371/journal.pone.0136089 |