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Engraftment of Human Glioblastoma Cells in Immunocompetent Rats through Acquired Immunosuppression
Transplantation of glioblastoma patient biopsy spheroids to the brain of T cell-compromised Rowett (nude) rats has been established as a representative animal model for human GBMs, with a tumor take rate close to 100%. In immunocompetent littermates however, primary human GBM tissue is invariably re...
Autores principales: | Huszthy, Peter C., Sakariassen, Per Ø., Espedal, Heidi, Brokstad, Karl A., Bjerkvig, Rolf, Miletic, Hrvoje |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546393/ https://www.ncbi.nlm.nih.gov/pubmed/26291724 http://dx.doi.org/10.1371/journal.pone.0136089 |
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