Cargando…

Endothelial Cell mTOR Complex-2 Regulates Sprouting Angiogenesis

Tumor neovascularization is targeted by inhibition of vascular endothelial growth factor (VEGF) or the receptor to prevent tumor growth, but drug resistance to angiogenesis inhibition limits clinical efficacy. Inhibition of the phosphoinositide 3 kinase pathway intermediate, mammalian target of rapa...

Descripción completa

Detalles Bibliográficos
Autores principales: Farhan, Maikel A., Carmine-Simmen, Katia, Lewis, John D., Moore, Ronald B., Murray, Allan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546419/
https://www.ncbi.nlm.nih.gov/pubmed/26295809
http://dx.doi.org/10.1371/journal.pone.0135245