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Endothelial Cell mTOR Complex-2 Regulates Sprouting Angiogenesis
Tumor neovascularization is targeted by inhibition of vascular endothelial growth factor (VEGF) or the receptor to prevent tumor growth, but drug resistance to angiogenesis inhibition limits clinical efficacy. Inhibition of the phosphoinositide 3 kinase pathway intermediate, mammalian target of rapa...
Autores principales: | Farhan, Maikel A., Carmine-Simmen, Katia, Lewis, John D., Moore, Ronald B., Murray, Allan G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546419/ https://www.ncbi.nlm.nih.gov/pubmed/26295809 http://dx.doi.org/10.1371/journal.pone.0135245 |
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