β-catenin activation drives thymoma initiation and progression in mice

Thymoma is the most commonly identified cancer in the anterior mediastinum. To date, the causal mechanism that drives thymoma progression is not clear. Here, we generated K5-ΔN64Ctnnb1/ER(T2) transgenic mice, which express an N-terminal deletion mutant of β-catenin fused to a mutated ligand-binding...

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Detalles Bibliográficos
Autores principales: Liang, Chih-Chia, Lu, Tsai-Ling, Yu, Yi-Ru, You, Li-Ru, Chen, Chun-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546445/
https://www.ncbi.nlm.nih.gov/pubmed/26101855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546445/
https://www.ncbi.nlm.nih.gov/pubmed/26101855

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