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β-catenin activation drives thymoma initiation and progression in mice
Thymoma is the most commonly identified cancer in the anterior mediastinum. To date, the causal mechanism that drives thymoma progression is not clear. Here, we generated K5-ΔN64Ctnnb1/ER(T2) transgenic mice, which express an N-terminal deletion mutant of β-catenin fused to a mutated ligand-binding...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546445/ https://www.ncbi.nlm.nih.gov/pubmed/26101855 |