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Deltex-3-like (DTX3L) stimulates metastasis of melanoma through FAK/PI3K/AKT but not MEK/ERK pathway

Deltex-3-like (DTX3L), an E3 ligase, is a member of the Deltex (DTX) family and is also called B-lymphoma and BAL-associated protein (BBAP). Previously, we established RFP/RET-transgenic mice, in which systemic hyperpigmented skin, benign melanocytic tumor(s) and melanoma(s) develop stepwise. Here w...

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Detalles Bibliográficos
Autores principales: Thang, Nguyen Dinh, Yajima, Ichiro, Kumasaka, Mayuko Y., Iida, Machiko, Suzuki, Tamio, Kato, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546467/
https://www.ncbi.nlm.nih.gov/pubmed/26033450