Fibroblast surface-associated FGF-2 promotes contact-dependent colorectal cancer cell migration and invasion through FGFR-SRC signaling and integrin α(v)β(5)-mediated adhesion

Carcinoma-associated fibroblasts were reported to promote colorectal cancer (CRC) invasion by secreting motility factors and extracellular matrix processing enzymes. Less is known whether fibroblasts may induce CRC cancer cell motility by contact-dependent mechanisms. To address this question we cha...

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Detalles Bibliográficos
Autores principales: Knuchel, Sarah, Anderle, Pascale, Werfelli, Patricia, Diamantis, Eva, Rüegg, Curzio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546468/
https://www.ncbi.nlm.nih.gov/pubmed/25973543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546468/
https://www.ncbi.nlm.nih.gov/pubmed/25973543

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