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Endoplasmic reticulum targeting in Ewing's sarcoma by the alkylphospholipid analog edelfosine

Ewing's sarcoma (ES) is the second most common bone cancer in children and young people. Edelfosine (1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine) is the prototype of a family of synthetic antitumor compounds, collectively known as alkylphospholipid analogs (APLs). We have found that A...

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Detalles Bibliográficos
Autores principales: Bonilla, Ximena, Dakir, EL-Habib, Mollinedo, Faustino, Gajate, Consuelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546490/
https://www.ncbi.nlm.nih.gov/pubmed/25999349