Dynamic treatment effect (DTE) curves reveal the mode of action for standard and experimental cancer therapies

We present a method for estimating the empirical dynamic treatment effect (DTE) curves from tumor growth delay (TGD) studies. This improves on current common methods of TGD analysis, such as T/C ratio and doubling times, by providing a more detailed treatment effect and overcomes their lack of repro...

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Detalles Bibliográficos
Autores principales: Choudhury, Kingshuk Roy, Keir, Stephen T., Ashcraft, Kathleen A., Boss, Mary-Keara, Dewhirst, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546495/
https://www.ncbi.nlm.nih.gov/pubmed/25986925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546495/
https://www.ncbi.nlm.nih.gov/pubmed/25986925

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