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Dynamic treatment effect (DTE) curves reveal the mode of action for standard and experimental cancer therapies

We present a method for estimating the empirical dynamic treatment effect (DTE) curves from tumor growth delay (TGD) studies. This improves on current common methods of TGD analysis, such as T/C ratio and doubling times, by providing a more detailed treatment effect and overcomes their lack of repro...

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Detalles Bibliográficos
Autores principales:	Choudhury, Kingshuk Roy, Keir, Stephen T., Ashcraft, Kathleen A., Boss, Mary-Keara, Dewhirst, Mark W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546495/ https://www.ncbi.nlm.nih.gov/pubmed/25986925

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