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Confinement-Induced Drug-Tolerance in Mycobacteria Mediated by an Efflux Mechanism

Tuberculosis (TB) is the world’s deadliest curable disease, responsible for an estimated 1.5 million deaths annually. A considerable challenge in controlling this disease is the prolonged multidrug chemotherapy (6 to 9 months) required to overcome drug-tolerant mycobacteria that persist in human tis...

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Detalles Bibliográficos
Autores principales: Luthuli, Brilliant B., Purdy, Georgiana E., Balagaddé, Frederick K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546595/
https://www.ncbi.nlm.nih.gov/pubmed/26295942
http://dx.doi.org/10.1371/journal.pone.0136231