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Confinement-Induced Drug-Tolerance in Mycobacteria Mediated by an Efflux Mechanism
Tuberculosis (TB) is the world’s deadliest curable disease, responsible for an estimated 1.5 million deaths annually. A considerable challenge in controlling this disease is the prolonged multidrug chemotherapy (6 to 9 months) required to overcome drug-tolerant mycobacteria that persist in human tis...
Autores principales: | Luthuli, Brilliant B., Purdy, Georgiana E., Balagaddé, Frederick K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546595/ https://www.ncbi.nlm.nih.gov/pubmed/26295942 http://dx.doi.org/10.1371/journal.pone.0136231 |
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