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Interferon-γ Promotes Inflammation and Development of T-Cell Lymphoma in HTLV-1 bZIP Factor Transgenic Mice

Human T-cell leukemia virus type 1 (HTLV-1) is an etiological agent of several inflammatory diseases and a T-cell malignancy, adult T-cell leukemia (ATL). HTLV-1 bZIP factor (HBZ) is the only viral gene that is constitutively expressed in HTLV-1-infected cells, and it has multiple functions on T-cel...

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Detalles Bibliográficos
Autores principales: Mitagami, Yu, Yasunaga, Jun-ichirou, Kinosada, Haruka, Ohshima, Koichi, Matsuoka, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546626/
https://www.ncbi.nlm.nih.gov/pubmed/26296091
http://dx.doi.org/10.1371/journal.ppat.1005120