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Brazilin Limits Inflammatory Responses through Induction of Prosurvival Autophagy in Rheumatoid Fibroblast-Like Synoviocytes

Brazilin is an active compound of Caesalpinia sappan L. (Leguminosae), which possesses pro-apoptotic and anti-inflammation potentials depending on the specific cell type. However, it is largely unknown whether autophagy is implicated in the mechanism underlying its chemotherapeutic and anti-inflamma...

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Detalles Bibliográficos
Autores principales: Lee, Hyunji, Kang, Seong Wook, Byun, Hee Sun, Jeon, Juhee, Park, Kyeong Ah, Kang, Kidong, Seo, Wonhyoung, Won, Minho, Seok, Jeong Ho, Han, Man-Deuk, Shen, Han-Ming, Hur, Gang Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546660/
https://www.ncbi.nlm.nih.gov/pubmed/26295477
http://dx.doi.org/10.1371/journal.pone.0136122