Cucurbitacin I Attenuates Cardiomyocyte Hypertrophy via Inhibition of Connective Tissue Growth Factor (CCN2) and TGF- β/Smads Signalings

Cucurbitacin I is a naturally occurring triterpenoid derived from Cucurbitaceae family plants that exhibits a number of potentially useful pharmacological and biological activities. However, the therapeutic impact of cucurbitacin I on the heart has not heretofore been reported. To evaluate the funct...

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Detalles Bibliográficos
Autores principales: Jeong, Moon Hee, Kim, Shang-Jin, Kang, Hara, Park, Kye Won, Park, Woo Jin, Yang, Seung Yul, Yang, Dong Kwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546681/
https://www.ncbi.nlm.nih.gov/pubmed/26296085
http://dx.doi.org/10.1371/journal.pone.0136236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546681/
https://www.ncbi.nlm.nih.gov/pubmed/26296085
http://dx.doi.org/10.1371/journal.pone.0136236

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