Behavior and Properties of Mature Lytic Granules at the Immunological Synapse of Human Cytotoxic T Lymphocytes

Killing of virally infected cells or tumor cells by cytotoxic T lymphocytes requires targeting of lytic granules to the junction between the CTL and its target. We used whole-cell patch clamp to measure the cell capacitance at fixed intracellular [Ca(2+)] to study fusion of lytic granules in human C...

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Detalles Bibliográficos
Autores principales: Ming, Min, Schirra, Claudia, Becherer, Ute, Stevens, David R., Rettig, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546685/
https://www.ncbi.nlm.nih.gov/pubmed/26296096
http://dx.doi.org/10.1371/journal.pone.0135994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546685/
https://www.ncbi.nlm.nih.gov/pubmed/26296096
http://dx.doi.org/10.1371/journal.pone.0135994

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