Exploiting the Fanconi Anemia Pathway for Targeted Anti-Cancer Therapy

Genome instability, primarily caused by faulty DNA repair mechanisms, drives tumorigenesis. Therapeutic interventions that exploit deregulated DNA repair in cancer have made considerable progress by targeting tumor-specific alterations of DNA repair factors, which either induces synthetic lethality...

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Detalles Bibliográficos
Autores principales: Jo, Ukhyun, Kim, Hyungjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2015
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546938/
https://www.ncbi.nlm.nih.gov/pubmed/26194820
http://dx.doi.org/10.14348/molcells.2015.0175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546938/
https://www.ncbi.nlm.nih.gov/pubmed/26194820
http://dx.doi.org/10.14348/molcells.2015.0175

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