Dephosphorylation of DBC1 by Protein Phosphatase 4 Is Important for p53-Mediated Cellular Functions

Deleted in breast cancer-1 (DBC1) contributes to the regulation of cell survival and apoptosis. Recent studies demonstrated that DBC is phosphorylated at Thr454 by ATM/ATR kinases in response to DNA damage, which is a critical event for p53 activation and apoptosis. However, how DBC1 phosphorylation...

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Detalles Bibliográficos
Autores principales: Lee, Jihye, Adelmant, Guillaume, Marto, Jarrod A., Lee, Dong-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546941/
https://www.ncbi.nlm.nih.gov/pubmed/26194823
http://dx.doi.org/10.14348/molcells.2015.0066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546941/
https://www.ncbi.nlm.nih.gov/pubmed/26194823
http://dx.doi.org/10.14348/molcells.2015.0066

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