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Mild hypoxia in vivo regulates cardioprotective SUR2A: A role for Akt and LDH
High-altitude residents have lower mortality rates for ischaemic heart disease and this is ascribed to cardiac gene remodelling by chronic hypoxia. SUR2A is a cardioprotective ABC protein serving as a subunit of sarcolemmal ATP-sensitive K(+) channels. The purpose of this study was to determine whet...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Pub. Co
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547089/ https://www.ncbi.nlm.nih.gov/pubmed/25576887 http://dx.doi.org/10.1016/j.bbadis.2015.01.001 |