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CAMKII-conditional deletion of histone deacetylase 2 potentiates acute methamphetamine-induced expression of immediate early genes in the mouse nucleus accumbens

Methamphetamine (METH) produces increases in the expression of immediate early genes (IEGs) and of histone deacetylase 2 (HDAC2) in the rat nucleus accumbens (NAc). Here, we tested whether HDAC2 deletion influenced the effects of METH on IEG expression in the NAc. Microarray analyses showed no basel...

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Detalles Bibliográficos
Autores principales: Torres, Oscar V., McCoy, Michael T., Ladenheim, Bruce, Jayanthi, Subramaniam, Brannock, Christie, Tulloch, Ingrid, Krasnova, Irina N., Cadet, Jean Lud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547138/
https://www.ncbi.nlm.nih.gov/pubmed/26300473
http://dx.doi.org/10.1038/srep13396