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Systemic Administration of siRNA via cRGD-containing Peptide

Although small interfering RNAs (siRNAs) have been demonstrated to specifically silence their target genes in disease models and clinical trials, in vivo siRNA delivery is still the technical bottleneck that limits their use in therapeutic applications. In this study, a bifunctional peptide named RG...

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Detalles Bibliográficos
Autores principales: Huang, Yuanyu, Wang, Xiaoxia, Huang, Weiyan, Cheng, Qiang, Zheng, Shuquan, Guo, Shutao, Cao, Huiqing, Liang, Xing-Jie, Du, Quan, Liang, Zicai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547141/
https://www.ncbi.nlm.nih.gov/pubmed/26300278
http://dx.doi.org/10.1038/srep12458