Cargando…
Systemic Administration of siRNA via cRGD-containing Peptide
Although small interfering RNAs (siRNAs) have been demonstrated to specifically silence their target genes in disease models and clinical trials, in vivo siRNA delivery is still the technical bottleneck that limits their use in therapeutic applications. In this study, a bifunctional peptide named RG...
Autores principales: | Huang, Yuanyu, Wang, Xiaoxia, Huang, Weiyan, Cheng, Qiang, Zheng, Shuquan, Guo, Shutao, Cao, Huiqing, Liang, Xing-Jie, Du, Quan, Liang, Zicai |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547141/ https://www.ncbi.nlm.nih.gov/pubmed/26300278 http://dx.doi.org/10.1038/srep12458 |
Ejemplares similares
-
Protective effect of Gelofusine against cRGD-siRNA-induced nephrotoxicity in mice
por: Liao, Wenjie, et al.
Publicado: (2018) -
Enhanced Intercellular Delivery of cRGD–siRNA
Conjugates by an Additional Oligospermine Modification
por: Nakamoto, Kosuke, et al.
Publicado: (2018) -
PAMAM-cRGD mediating efficient siRNA delivery to spermatogonial stem cells
por: Li, Tianjiao, et al.
Publicado: (2019) -
cRGD peptide-conjugated polyethylenimine-based lipid nanoparticle for intracellular delivery of siRNA in hepatocarcinoma therapy
por: Yang, Shuang, et al.
Publicado: (2021) -
Tumor-targeted in vivo gene silencing via systemic delivery of cRGD-conjugated siRNA
por: Liu, Xiaoxia, et al.
Publicado: (2014)