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The Conformation of Myosin Heads in Relaxed Skeletal Muscle: Implications for Myosin-Based Regulation

In isolated thick filaments from many types of muscle, the two head domains of each myosin molecule are folded back against the filament backbone in a conformation called the interacting heads motif (IHM) in which actin interaction is inhibited. This conformation is present in resting skeletal muscl...

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Detalles Bibliográficos
Autores principales: Fusi, Luca, Huang, Zhe, Irving, Malcolm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547144/
https://www.ncbi.nlm.nih.gov/pubmed/26287630
http://dx.doi.org/10.1016/j.bpj.2015.06.038