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The Conformation of Myosin Heads in Relaxed Skeletal Muscle: Implications for Myosin-Based Regulation
In isolated thick filaments from many types of muscle, the two head domains of each myosin molecule are folded back against the filament backbone in a conformation called the interacting heads motif (IHM) in which actin interaction is inhibited. This conformation is present in resting skeletal muscl...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547144/ https://www.ncbi.nlm.nih.gov/pubmed/26287630 http://dx.doi.org/10.1016/j.bpj.2015.06.038 |