Mitochondrial uncoupling protein-2 is not involved in palmitate-induced impairment of glucose-stimulated insulin secretion in INS-1E insulinoma cells and is not needed for the amplification of insulin release

We have recently shown that overnight exposure of INS-1E insulinoma cells to palmitate in the presence of high glucose causes defects in both mitochondrial energy metabolism and glucose-stimulated insulin secretion (GSIS). Here we report experiments designed to test the involvement of mitochondrial...

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Detalles Bibliográficos
Autores principales: Hirschberg Jensen, Verena, Affourtit, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547158/
https://www.ncbi.nlm.nih.gov/pubmed/26339685
http://dx.doi.org/10.1016/j.bbrep.2015.03.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547158/
https://www.ncbi.nlm.nih.gov/pubmed/26339685
http://dx.doi.org/10.1016/j.bbrep.2015.03.008

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